Systane Ultra
If I had to settle on just one eye drop, this would be it. While it's probably the most expensive, it is by the far the best one I've ever used in every way possible. It eliminates the redness, moisturizes and most notably its longer lasting than virtually everything else I've tried.
The solution feels slightly "thick" compared to your typical eye drop. When applied, it sort of coats your eyes and feels a bit different than the cheaper stuff. It's not unpleasant, and after a few blinks your eyes feel great.
The fact that it lasts so much longer than conventional drops is what really sets if apart. I typically only need to use it a couple times a day, or less. On a particularly bad dry eye day, using something like Tears would require numerous applications during the course of the day. Not the case with Systane Ultra. This stuff works.
Rohto
This unique Japanese eye drop provides good moisture and does an excellent job of removing redness and making your eyes as white as snow. However, its most notable quality is its "cooling kick" that provides relief for tired, strained eyes.
They make a few different drops with varied levels of coolness but be warned, they can be intense for first time users or people who have sensitive eyes. Its always amusing to watch people's first time reaction to using these eye drops, a lot of people say they sting, or are just very cold feeling but generally a few blinks later they admit their eyes feel good. However, a few people I've seen try them just don't like how cool they feel.
Once you get used to the initial sensation of applying them, I think the end result feels really good on tired eyes. Plus, they are pretty fun to share with unsuspecting friends as well.
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